The National Heart, Lung, and Blood Institute (NHLBI) and National Human Genome Research Institute (NHGRI) have funded a new program known as the Exome Project. The goal of this project is to develop cost-effective, high-throughput sequencing of the protein coding regions of the human genome for application in well-phenotyped populations. Three groups are currently funded to test and implement approaches in four key areas - sample preparation, target capture, sequencing, and data management and analysis - to generate an integrated resequencing pipeline with the potential to reduce the cost of exome analysis.
Current Exome Project Participants
Broad Institute
Stacey Gabriel
Chad Nusbaum
Harvard Medical School
George Church
Jonathan Seidman
Kun Zhang
University of Washington
Deborah Nickerson
Jay Shendure
Phil Green
Evan Eichler
NHLBI
Weiniu Gan
Alan Michelson
Deborah Applebaum-Bowden
NHGRI
Lu Wang
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