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The Exome Project

The National Heart, Lung, and Blood Institute (NHLBI) and National Human Genome Research Institute (NHGRI) have funded a new program known as the Exome Project. The goal of this project is to develop cost-effective, high-throughput sequencing of the protein coding regions of the human genome for application in well-phenotyped populations. Three groups are currently funded to test and implement approaches in four key areas - sample preparation, target capture, sequencing, and data management and analysis - to generate an integrated resequencing pipeline with the potential to reduce the cost of exome analysis.

Current Exome Project Participants

Broad Institute

Stacey Gabriel

Chad Nusbaum

Harvard Medical School

George Church

Jonathan Seidman

Kun Zhang

University of Washington

Deborah Nickerson

Jay Shendure

Phil Green

Evan Eichler


Weiniu Gan

Alan Michelson

Deborah Applebaum-Bowden


Lu Wang